Cancer treatment is becoming increasingly personalized, and technologies now allow patients to access methods that were unavailable just a few decades ago. One such innovation is HIPEC (Hyperthermic Intraperitoneal Chemotherapy), which is currently considered one of the most effective approaches for treating various abdominal cancer conditions.

What is HIPEC and how does it work?

HIPEC is a combined method that integrates surgical removal of cancerous tissues (cytoreductive surgery) with the subsequent introduction of a heated chemotherapeutic solution directly into the abdominal cavity. The heated solution (up to 41–43°C) circulates for 60–90 minutes, allowing not only for the destruction of remaining cancer cells but also minimizing their future spread.

Why heat?

Heating enhances the effect of chemotherapy agents, increasing their penetration into tissues and reducing the resistance of tumor cells. This is twice as effective as traditional systemic chemotherapy, as the concentrated impact occurs exactly where it is needed.

When is HIPEC used?

HIPEC is used in the treatment of peritoneal carcinomatosis—a condition where cancer cells spread along the inner lining of the abdominal cavity. It is most commonly associated with cancers such as:

  • colorectal cancer;
  • ovarian cancer;
  • peritoneal mesothelioma;
  • pseudomyxoma peritonei.

This method is effective when other forms of treatment are less successful. According to studies, the 5-year survival rate for patients with peritoneal carcinomatosis from colorectal cancer after HIPEC reaches 50-60%, whereas with standard approaches, it rarely exceeds 15-20%.

Advantages of the HIPEC method

Local impact: unlike systemic chemotherapy, the drug acts directly in the abdominal cavity, reducing the load on other organs and systems. Minimization of recurrences: removing visible tumors combined with chemical treatment reduces the risk of the disease reappearing. Increased survival: this method has proven effective in extending the lives of patients, especially in late stages of the disease. Fewer side effects: thanks to the local application of the drug, its toxicity to the entire body is minimized.

Alisa Health Group provides access to advanced treatment methods like HIPEC in the world's leading medical centers. We collaborate with clinics specializing in oncology where leading experts in cytoreductive surgery and hyperthermic chemotherapy work.

How can we help?

Expert consultation: we will help you understand if the HIPEC method is suitable for you and organize a meeting with doctors specializing in this approach. Clinic selection: we will select a medical institution where HIPEC is performed at the highest level, using the latest equipment. Support in organizing treatment: we will take care of logistics, including flights, accommodation, and translation of medical documents. Support at all stages: our team will be with you from the initial consultation to the completion of treatment and recovery, ensuring maximum comfort.

What does practice say?

According to data from the US National Cancer Institute, HIPEC can increase the average life expectancy of patients with peritoneal mesothelioma to 53 months, whereas without it, it is no more than 12-16 months. Additionally, a 2021 meta-analysis showed that in patients with ovarian cancer who underwent HIPEC, the likelihood of recurrence is reduced by 31%.

Understanding and support come first

We understand that cancer treatment is not only a medical process but also an emotional challenge. Therefore, the specialists at Alisa Health Group not only organize your treatment but also provide support, helping you and your loved ones at every step.

If you want to learn more about the HIPEC method, its advantages, and its applicability in your case, Alisa Health Group is ready to be your guide to modern and effective treatment.

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